Clinical trial: levofloxacin-based quadruple therapy was inferior to traditional quadruple therapy in the treatment of resistant Helicobacter pylori infection
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چکیده
منابع مشابه
Levofloxacin-based triple therapy vs. quadruple therapy in second-line Helicobacter pylori treatment: a randomized trial.
BACKGROUND Levofloxacin has been shown to be effective in Helicobacter pylori eradication. Two 10-day levofloxacin-based triple therapies were compared with standard 7- and 14-day quadruple regimens in second-line treatment. METHODS Two hundred and eighty consecutive patients who failed to respond to standard triple therapy (clarithromycin, amoxicillin, rabeprazole) were randomly assigned to ...
متن کامل1-day quadruple therapy was not inferior to 7-day triple therapy for eradication of Helicobacter pylori infection in dyspepsia.
P a t i e n t s 160 patients ≥ 18 years of age (mean age 50 y, 57% women) with dyspepsia and H. pylori infection who had a Glasgow Dyspepsia Severity Score (GDSS) of ≥ 3 (score range 0 to 20) and a positive carbon 14 urea breath test result. Exclusion criteria included previous treatment of H. pylori infection, pregnancy, personal or family history of gastrointestinal malignancy, antibiotic the...
متن کاملThe efficacy of furazolidone-based quadruple therapy for eradication of Helicobacter pylori infection in Iranian patients resistant to metronidazole-based quadruple therapy.
BACKGROUND Furazolidone has recently shown promising efficacy in H. pylori eradication and has replaced metronidazole in different eradication regimens especially in countries, like Iran, with high prevalence of metronidazole resistance and where clarithromycin is expensive and hardly available. This study tries to determine the efficacy of a quadruple therapy based on furazolidone as a second ...
متن کاملLevofloxacin/amoxicillin-based schemes vs quadruple therapy for Helicobacter pylori eradication in second-line.
Worldwide prevalence of Helicobacter pylori (H. pylori) infection is approximately 50%, with the highest being in developing countries. We compared cure rates and tolerability (SE) of second-line anti-H. pylori levofloxacin/amoxicillin (LA)-based triple regimens vs standard quadruple therapy (QT). An English language literature search was performed up to October 2010. A meta-analysis was perfor...
متن کاملclarithromycin vs. gemifloxacin in quadruple therapy regimens for empiric primary treatment of helicobacter pylori infection: a randomized clinical trial
background : eradication of helicobacter pylori infection plays a crucial role in the treatment of peptic ulcer. clarithromycin resistance is a major cause of treatment failure. this randomized clinical trial aimed at evaluating the efficacy of a clarithromycin versus gemifloxacin containing quadruple therapy regimen in eradication of h. pylori infection. methods : in this randomized double bli...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2007
ISSN: 0269-2813,1365-2036
DOI: 10.1111/j.1365-2036.2007.03452.x